Loratadine is also effective in idiopathic chronic urticaria. In children over 2 years, Loratadine is indicated for the symptomatic relief of seasonal allergic rhinitis and allergic skin conditions such as urticaria nettle rash.
Dosage & Administration
- 2-12 years (body weight more than 30 Kg): 10 mg Loratadine once daily.
- 2-12 years (body weight less than 30 Kg): 5 mg Loratadine once daily.
- Below 2 years of age: Safety and efficacy of Loratadine have not been established.
Liver & renal impairment: Patients with liver impairment and renal insufficiency (GFR <30 ml/min) should be given a lower initial dose (10 mg every other day).
Pregnancy & Lactation
Use in lactation: Loratadine is excreted in breast milk, so it should not be administered to lactating mother.
Management: Symptomatic and supportive treatment. Immediately empty stomach by inducing emesis with ipecac syrup. Admin of activated charcoal after emesis may be useful. If induction of vomiting is unsuccessful or contraindicated (e.g. patient is comatose, having seizures or lacks gag reflex), gastric lavage with NaCl 0.9% soln may be performed to prevent aspiration of gastric contents. Saline cathartics may be useful to rapidly dilute bowel contents.