Dosage & Administration
Adults: The recommended dosage of Efavirenz is 600 mg orally, once daily, in combination with a protease inhibitor and/or nucleoside analogue reverse transcriptase inhibitors (NRTIs).
Pediatric Patients: Following table describes the recommended dose of Efavirenz for pediatric patients 3 years of age or older and weighing between 10 and 40 kg. The recommended dosage of Efavirenz for pediatric patients weighing greater than 40 kg is 600 mg, once daily.
10 to <15 kg: 200 mg
15 to < 20 kg: 250 mg
20 to < 25 kg: 300 mg
25 to < 32.5 kg: 350 mg
32.5 to < 40 kg: 400 mg
40 kg: 600 mg
Pregnancy & Lactation
Lactation: Efavirenz may pass through breast milk and cause serious harm to the baby. It should not be used during lactation.
Management: Supportive and symptomatic treatment. May administer activated charcoal.
Use in Special Population
Women taking hormone-based birth control: Women should not rely only on hormone-based birth control, such as pills, injections, or implants, because Efavirenz may make these contraceptives ineffective.